Ex parte BONFILS et al. - Page 3




                   Appeal No. 2001-2138                                                                                                                             
                   Application No. 08/403,276                                                                                                                       


                                      3.        The naturally occurring steroid estrone has the following                                                           
                   stereochemistry:                                                                                                                                 












                   (FIESER at 464.)                                                                                                                                 
                                      An atom or group that lies below the plane of the paper is depicted by a                                                      
                   dashed line leading to the group, and denoted “"” in the chemical name.  An atom or                                                              
                   group that lies above the plane of the paper is depicted by a solid line, dark triangles or                                                      

                   thickened lines leading to the group, and denoted “$” in the chemical name.  (May at 1085,                                                       

                   197 USPQ at 603.)  Bonds to atoms or groups that can lie above or below the plane of the                                                         
                   paper are denoted by wavy lines.  (Spec. at 3, ll.6–9.)                                                                                          










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