Ex parte BONFILS et al. - Page 6




                   Appeal No. 2001-2138                                                                                                                             
                   Application No. 08/403,276                                                                                                                       


                            atoms, n is an integer from 2 to 15, R  is alkyl of 1 to 12 carbon atoms, R  is4                                             5                               
                            selected from the group consisting of hydrogen, alkyl of 1 to 12 carbon                                                                 
                            atoms and acyl of an organic carboxylic acid of up to 12 carbon atoms and                                                               
                            the wavy lines indicate that the 17- and 20- asymmetrical centers are                                                                   
                            independent of the absolute R and S configurations and their non-toxic,                                                                 
                            pharmaceutically acceptable acid addition salts.                                                                                        
                                                               The examiner’s rejections                                                                            
                                      10.       Claims 1 through 5 were rejected under 35 U.S.C. § 103(a) as being                                                  
                   unpatentable over French patent document 1,380,424 (“RUSI”), or French patent document                                                           
                   90,805 (“RUSII”), both assigned to RousselSUclaf.  On receipt by the board, no translation                                                       
                   for either document was present in the application file.                                                                                         
                                                                      RousselSUclaf I                                                                               
                                      11.       U.S. Patent No. 3,156,619, issued to Bertin and Nedélec on                                                          
                   November 10, 1964 (“Bertin”), claims priority in part from RUSI.  Although Bertin contains                                                       

                   material not included in RUSI, the parallel cites post confirm the sense of the French text.                                                     

                   We stress that the examiner did not cite Bertin, and that we use it as an informal translation                                                   
                   to confirm our reliance on chemical formulas and names disclosed by RUS1.                                                                        








                                      12.       RUSI concerns compounds having the structure:                                                                       

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