Ex Parte Pugliese - Page 9



          Appeal No. 2005-0545                                                         
          Application No. 09/989,019                                                   

               Soudant teaches the topical application or oral administration          
          of multicomponent anticellulitic compositions including at least one         
          lipolytic agent thought to erase local accumulation of fat for use           
          in combating cellulitis, eliminating local fat overload, and                 
          slimming (Soudant: cols. 1-2).  Soudant’s compositions may include           
          one or more lipolytic agents selected from a group including                 
          xanthines and carnitine (Soudant, col. 2, l. 27-42).                         
               Koulbanis teaches the topical application of multicomponent             
          cosmetic compositions having slimming and anti-cellulitis action             
          including at least one xanthine.  Xanthines selected from                    
          theophylline, caffeine and theobromine are thought by Koulbanis to           
          erase local accumulation of fat by increasing lipolytic action and           
          thus be useful for treating skin with rolls of fat and cellulitis            
          (Koulbanis, cols. 3, l. 47-51).                                              
               Sekiya teaches percutaneous (Sekiya, col. 2, l. 1-3 and 49              
          (application onto skin)) or oral administration of multicomponent            
          compositions (Sekiya, col. 1, l. 55-59) including at least one               
          isoflavone which is said to promote fat-degradation and weight               
          reduction (Sekiya, cols. 1-2).                                               
               Majeed teaches topical or oral administration (Majeed, col. 4,          
          l. 47-49) of compositions containing a forskohlin extract from the           
          Coleus Forskohli plant and other nutritional supplements (Majeed,            
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