Appeal No. 2006-2248
Application No. 10/158,618
useful in the compositions of the present invention include butylated
hydroxytoluene (BHT), ascorbyl palmitate, butylated hydroxyanisole (BHA), a-
tocopherol, phenyl-a-naphthylamine, hydroquinone, propyl gallate,
nordihydroguiaretic acid, and mixtures thereof as well as any other known oil-
soluble antioxidant compatible with the other components of the compositions.
(col. 6, lines 22-31).
9. The oil-soluble antioxidants useful in the compositions of this
invention should be utilized in a stabilizing effective amount and may range in
total from about 0.001 to about 5% based on the weight of the total composition,
preferably from about 0.01 to about 1%. The amount of antioxidants utilized in the
compositions of the present invention is dependent in part on the specific
antioxidants selected, the amount of and specific retinoid being protected and the
processing conditions. For example, a retinol formulation should include BHT in
the amount of from about 0.01% to about 1% by weight. A retinal formulation
should include BHT in the amount of from about 0.01% to about 1% by weight
(col. 6, lines 32-44).
10. The compositions of this invention may also include a chelating
agent to minimize metal ion contamination. The retinoid compounds of this
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