Ex Parte Kalghatgi et al - Page 9


                Appeal No.  2006-2493                                                   Page 9                 
                Application No.  10/126,122                                                                    
                      We also recognize the examiner’s assertion (Answer, page 10) “that                       
                C[arell] teaches on page 173 that his synthetic method is specifically designed to             
                produce compounds wherein ‘nearly all’ possess a unique molecular weight. . . .”               
                While it is true that Carell teaches (page 173, column 2), “[w]ith the help of a               
                simple computer program, the building blocks were grouped in sets such that                    
                nearly all of the compounds produced from a given set would possess a unique                   
                molecular weight,” a complete reading of the paragraph that includes this                      
                statement reveals that the statement was made in the context of a “model                       
                library.”  Accordingly, we are not persuaded by the examiner’s intimation that                 
                “nearly all” of the compounds present in the “screening libraries” taught by Carell            
                possess a unique molecular weight.                                                             
                      Lastly, we recognize the examiner’s conclusion (Answer, bridging                         
                paragraph, pages 10-11) “that C[arell] teaches/makes obvious a library                         
                comprising at least 250 compounds wherein each compound is different and                       
                ‘nearly all’ are expected to have a unique molecular weight . . . .”  The library to           
                which the examiner relies on, however, is a “model library,” which as taught by                
                Carell is not screened and is used only to analyze the efficiency of the synthetic             
                reactions prior to the production of a larger “screening library.”  As discussed               
                above these larger “screening libraries” are not mass-coded, and it fact Carell                
                expressly teaches that coding schemes were not used for the “screening library.”               
                Carell, page 172, first column.                                                                


                                                                                                               
                were “mass-coded.”  As discussed above, as we understand it, Carell expressly states that they 
                were not.                                                                                      





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