Ex Parte Lee - Page 7

                Appeal 2007-1033                                                                               
                Application 10/091,061                                                                         

                are drawn to treating cancer, which is construed as both inhibition and                        
                regression of cancer” (id.).                                                                   
                      We do not agree with the Examiner that the Declaration fails to                          
                overcome the prima facie case.  First, “commensurate in scope” means that                      
                the evidence provides a reasonable basis for concluding that the untested                      
                embodiments encompassed by the claims would behave similarly to the                            
                tested embodiment(s).  See In re Lindner, 457 F.2d 506, 508, 173 USPQ                          
                356, 358 (CCPA 1972) (“Here, only one mixture of ingredients was tested.                       
                . . .  The claims, however, are much broader in scope, . . . and we have to                    
                agree with the Patent Office that there is no ‘adequate basis for reasonably                   
                concluding that the great number and variety of compositions included by                       
                the claims would behave in the same manner as the [single] tested                              
                composition.’”) (bracketed material in original).                                              
                      In this case, the Examiner has not provided any reason why, in view                      
                of the Declaration, a synergistic effect would not also be expected for other                  
                cancers and at different dosages.  In this regard, we note that Vite generally                 
                teaches that compounds of formula V, which encompasses Compound 1, are                         
                “useful in the treatment of a variety of cancers,” including carcinoma of the                  
                breast, colon, lung, ovary, and pancreas (Vite 8).  In addition, we agree with                 
                Appellant that results demonstrating delay in tumor growth (as opposed to                      
                regression of cancer) are sufficient to demonstrate an effective cancer                        
                treatment (Reply Br. 8).                                                                       
                      Thus, we conclude that the Declaration provides sufficient evidence of                   
                an unexpectedly superior result to overcome the Examiner’s prima facie case                    
                of obviousness.                                                                                


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