Ex Parte Lee - Page 12

                Appeal 2007-1033                                                                               
                Application 10/091,061                                                                         

                1688 (Fed. Cir. 1995)).)  Soni does not support the proposition that                           
                unsupported or conclusory statements are sufficient to overcome a prima                        
                facie case of obviousness.  See Soni, 54 F.3d at 750, 34 USPQ2d at 1687                        
                (quoting, e.g., In re De Blauwe, 736 F.2d 699, 705, 222 USPQ 191, 196                          
                (Fed. Cir. 1984) (“‘Mere argument or conclusory statements . . . does not                      
                suffice.’”)).  In essence, the majority’s broad reading of Soni would put into                 
                place a “new rule” that would permit an applicant to overcome a prima facie                    
                case by merely showing “‘substantially improved results’” and stating that                     
                the results were “‘unexpected.’”  Soni, 54 F.3d at 755, 34 USPQ2d at 1691-                     
                92 (Michel, J., dissenting) (quoting 54 F.3d at 751, 34 USPQ2d at 1688) (the                   
                same language quoted and relied upon by the majority (supra p. 6)).  Such a                    
                test would “eliminate[] the applicant’s burden of coming forward with                          
                objective evidence of unexpectedness” and “may be inherently unworkable.”                      
                Id., 34 USPQ2d at 1692 (Michel, J., dissenting).                                               
                      Further, in Soni, the issue of whether the data were commensurate in                     
                scope with the claims was raised for the first time on appeal, and the court                   
                refused to consider it.  Id. at 751, 34 USPQ2d at 1688.                                        
                      Appellant has claimed a method reciting the combination of two prior                     
                art compounds known to be useful in treating cancer for that “very same                        
                purpose.”  (Answer 7.)  Given this situation, the majority properly found the                  
                Examiner had made a prima facie case of obviousness.  The majority also                        
                properly found “there would have been a reasonable expectation that                            
                administering capecitabine in combination with Compound 1 would provide                        
                a greater anti-cancer effect than would administering either capecitabine or                   
                Compound 1 alone” (see supra p.5).  Yet the majority decision will likely                      


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