Ex parte CACECI et al. - Page 3




          Appeal No. 94-3056                                                           
          Application 07/812,421                                                       


          Gourlie et al. (Gourlie), “Winter Flounder Antifreeze Pro-                   
          teins: A Multigene Family,” J. Biol. Chem., Vol. 259, No. 23,                
          pages 14960-14965 (1984).                                                    
          Peters et al. (Peters), “Biosynthesis of Winter Flounder                     
          Antifreeze Proprotein in E. coli,” Protein Eng., Vol. 3, pages               
          145-151 (1989).                                                              
          Scott et al. (Scott), “Structural Variations in the Alanine-                 
          Rich Antifreeze Proteins of the Pleuronectinae,” Eur. J.                     
          Biochem., Vol. 168,  pages 629-633 (1987).                                   

          Gupta et al. (Gupta), “Biological Limitations On the Length of               
          Highly Repetitive DNA Sequences That May Be Stably Maintained                
          Within Plasmid Replicons in Escherichia coli, BioTechnology,                 
          pages 602-609, September 1983.                                               
          Chakrabartty et al., (Chakrabartty), Structure-Function                      
          Relationship In A Winter Flounder Antifreeze Polypeptide,”                   
          J. Biol. Chem., Vol. 265, pages 11313-11316 (1989).                          
          Williams et al. (Williams), WO 88/05082, July 14, 1988.                      
          Ferrari et al. (Ferrari), WO 88/03533, May 19, 1988.                         
          Shen, Multiple Joined Genes Prevent Product Degradation in                   
          Escherichia coli, Proc. Natl. Acad. Sci., Vol. 81, pages 4627-               
          4631 (August 1984).                                                          
          Doel et al. (Doel), “The Expression in E. coli of Synthetic                  
          Repeating Polymeric Genes Coding For Poly(L-Aspartyl-L-                      
          Phenylalanine), Nucl. Acids Res., Vol. 8, No. 20, pages 4575-                
          4592                                                                         
          (September 1980).                                                            
          Kempe et al. (Kempe), “Multiple-Copy Genes: Production and                   
          Modification of Monomeric Peptides From Large Multimeric                     
          Fusion Proteins, Gene, Vol. 39, pages 239-245 (1985).                        


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