Ex parte RUDNICK et al. - Page 4




          Appeal No. 95-1640                                                          
          Application 07/752,138                                                      


          Gore and Associates, Inc. v. Garlock, Inc., 721 F.2d 1540,                  
          1554, 220 USPQ 303, 313 (Fed. Cir. 1983); and Kalman v.                     
          Kimberly-Clark Corp., 713 F.2d 760, 772, 218 USPQ 781, 789                  
          (Fed. Cir. 1983).                                                           
               The examiner also alleges that this same expression                    
          "similarly substituted naphthalenes and anthracenes" would                  
          have rendered obvious to one of ordinary skill in the art the               
          use of a thianthrene reactant.                                              
               It is true that when chemical compounds have "very close"              
          structural similarities and similar utilities, without more a               
          prima facie case may be made.  See for example In re Wilder,                
          563 F.2d 457, 460, 195 USPQ 426, 429 (CCPA 1977) (adjacent                  
          homologues and structural isomers); In re May, 574 F.2d 1082,               
          1090, 197 USPQ 601, 607 (CCPA 1978) (steroisomers); In re                   
          Hoch, 428 F.2d 1341, 1342, 166 USPQ 406, 408 (CCPA 1970) (acid              
          and ethyl ester).  However, where as here Forbus is directed                
          to polynuclear aromatic compounds and applicants' thianthrene               
          is a heterocyclic ring structure, there must be adequate                    
          support in the prior art for the equivalence between the                    
          aromatic naphthalene and anthracene and heterocyclic                        
          thianthrene in order to establish a prima facie case and shift              
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