Ex parte ANIMATI et al. - Page 4




                 Appeal No. 95-2727                                                                                                                    
                 Application 07/699,898                                                                                                                



                 1-8 of Bargiotti which set forth in vitro and in vivo data concerning the efficacy of those                                           
                 compounds as antitumor agents.                                                                                                        
                          Upon return of the application, the examiner should review the claimed invention                                             
                 in light of the disclosure of Bargiotti and all other relevant prior art and determine                                                
                 whether one of ordinary skill in the art would have found it obvious to form the 8-fluoro                                             
                 analogs of the compounds of Bargiotti.  The examiner should make the results of that                                                  
                 determination of record by issuing an appropriate office action.  We note in passing                                                  
                 that the comparison set forth in the declaration filed under 37 CFR § 1.132 is based                                                  
                 upon comparing the efficacy of compounds according to the present invention with                                                      
                 doxorubicin, not the compounds of Bargiotti.  The compounds of Bargiotti are closer                                                   
                 prior art than doxorubicin.                                                                                                           
                                                                   REVERSED                                                                            


                                            Sherman D. Winters                                   )                                                     
                                            Administrative Patent Judge                          )                                                     
                                                                                                 )                                                     
                                                                                                 )                                                     
                                                                                                 ) BOARD OF PATENT                                     
                                            William F. Smith                                     )                                                     
                                            Administrative Patent Judge                          )   APPEALS AND                                       
                                                                                                 )                                                     
                                                                                                 ) INTERFERENCES                                       
                                                                                                 )                                                     
                                            Fred E. McKelvey, Senior                             )                                                     
                                            Administrative Patent Judge                          )                                                     
                                                                          4                                                                            





Page:  Previous  1  2  3  4  5  Next 

Last modified: November 3, 2007