KEITH et al. V. COELHO - Page 11




          Interference No. 103,270                                                    



          (CR-11).  Coelho then states that prior to the meeting he                   
          conceived of a new procedure for performing a catheter                      
          exchange (CR-12):                                                           
                    That procedure involved provision of a                            
                    mechanism to inhibit movement of the                              
                    standard length (about 170-185 cm)                                
                    indwelling guidewire relative to the guide                        
                    catheter and, while maintaining the                               
                    guidewire in that position, first                                 
                    withdrawing the indwelling over-the-wire                          
                    catheter, then separating it from the                             
                    guidewire and, finally, threading a new                           
                    catheter onto the guidewire and advancing                         
                    it through the guide catheter and along the                       
                    guidewire.  I considered several ways of so                       
                    engaging the wire, including mechanisms by                        
                    which a balloon could be inflated within                          
                    the                                                               
                    guide catheter to engage and grip securely                        
                    an exposed portion of the guidewire within                        
                    the guide catheter.                                               
                    Coelho further testified that he disclosed and                    
          explained his idea to Enger prior to the meeting (id.).  Enger              
          likewise testified at CR-157 that:                                          
                    3.  Some time before December 2, 1988,                            
                    Mr. Coelho disclosed to me an idea that he                        
                    had to                                                            


                    facilitate catheter exchange of an over-                          
                    the-wire angioplasty catheter without                             
                    requiring the use of exchange wires,                              
                    extension wires or monorail catheters.  He                        
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