Interference No. 103,270 (CR-11). Coelho then states that prior to the meeting he conceived of a new procedure for performing a catheter exchange (CR-12): That procedure involved provision of a mechanism to inhibit movement of the standard length (about 170-185 cm) indwelling guidewire relative to the guide catheter and, while maintaining the guidewire in that position, first withdrawing the indwelling over-the-wire catheter, then separating it from the guidewire and, finally, threading a new catheter onto the guidewire and advancing it through the guide catheter and along the guidewire. I considered several ways of so engaging the wire, including mechanisms by which a balloon could be inflated within the guide catheter to engage and grip securely an exposed portion of the guidewire within the guide catheter. Coelho further testified that he disclosed and explained his idea to Enger prior to the meeting (id.). Enger likewise testified at CR-157 that: 3. Some time before December 2, 1988, Mr. Coelho disclosed to me an idea that he had to facilitate catheter exchange of an over- the-wire angioplasty catheter without requiring the use of exchange wires, extension wires or monorail catheters. He 11Page: Previous 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 NextLast modified: November 3, 2007