Appeal No 94-2912
Application 07/752,831
being added to said sucralfate in an amount
sufficient to form a paste;
(b) the mixture is allowed to dry; and
(c) the resulting material is dispersed in an
aqueous methylcellulose medium;
and wherein said preparation is topically applied
to said aphthous ulcer in and amount sufficient to
cover said aphthous ulcer.
23. A process of preparing a pharmaceutical preparation
for treatment of an aphthous ulcer, the process
comprising:
(a) triturating sucralfate powder with an aqueous
mixture of carboxypolymethylene, polysorbate-80
and simethicone to form a substantially
homogenous mixture, said aqueous mixture being
added to said sucralfate in an amount
sufficient to form a paste;
(b) allowing said substantially homogenous mixture
to dry into a gelatinous material; and
(c) mixing said gelatinous material with an aqueous
methylcellulose medium to form a preparation for
topical application to said aphthous ulcer.
We have reviewed appellants’ specification for everything
that it teaches persons having ordinary skill in the art. We
have considered appellants’ examples and all of the claims.
We have studied the combined teachings of the prior art cited
and applied against appellants’ claims. We have reviewed the
Declaration of David W. Pehrson, filed December 3, 1992,
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