Ex parte CAMPBELL - Page 7




                  Appeal No. 94-3187                                                                                                                      
                  Application 07/939,556                                                                                                                  


                  high virus yields, Bosch, considered in its entirety, indicates to us that the results to be                                            
                  obtained from an influenza virus infection of cells in culture at the time of the present                                               
                  invention was unpredictable.  This determination is consistent with appellant’s                                                         
                  characterization of the prior art at page 4, lines 3-14, of the specification referred to above.                                        


                           When we consider the entire record, it is our view that one of ordinary skill in the art                                       
                  at the time of the present invention would not have reasonably expected that a reassorted                                               
                  virus derived from equine influenza virus and PR8 and containing the RNA’s required by                                                  
                  the claims on appeal would be capable of growing in cell culture.                                                                       










                           The decision of the examiner is reversed.                                                                                      
                                                                    REVERSED                                                                              




                                                                                                   )                                                      
                                             WILLIAM F. SMITH                                      )                                                      

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