Ex parte TESHIMA et al. - Page 9




          Appeal No. 95-2088                                                          
          Application 08/056,882                                                      


          amounts of the claimed compounds were well known in the art at              
          the time the application was filed.                                         
               Second, for a showing of unexpected results to be                      
          probative evidence of nonobviousness, the appellant must                    
          establish (i) that there is a difference between the results                
          obtained for the claimed invention and those of the prior art,              
          and (ii) that the difference obtained is significant and would              
          not have been expected by a person having ordinary skill in                 
          the art at the time the invention was made.  In re Freeman,                 
          474 F.2d 1318, 1324, 177 USPQ 139, 143 (CCPA 1973); In re                   
          D'Ancicco, 439 F.2d 1244, 169 USPQ 303 (CCPA 1971).  This the               
          appellants have not done.                                                   
               An efficacy enhancer by definition is a compound which                 
          enhances, or increases, the effectiveness of another compound.              
          Therefore, it is reasonable to conclude that those skilled in               
          the art would have expected that a compound known to increase               
          the effectiveness of termite-controlling agents, in general,                
          and of                                                                      
          fenvalerate, in particular, would result in an increased                    
          mortality rate in termites when applied to the soil.  We                    


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