Ex parte ROSE et al. - Page 4




          Appeal No. 95-2960                                                          
          Application 08/009,381                                                      


          tubing segments used in dialysis or transfusion, to permit                  
          sterile fluid flow between them (col. 3, lines 15-20; col. 6,               
          lines 23-24).  The rubber tubing segments are connected by a                
          conductive metal tube which has male and female portions (col.              
          5, line 40 - col. 6, line 10).   When a dialysis bag is                     
          replaced, the male and female portions of the conductive metal              
          tube are                                                                    




          sterilized with an alcohol lamp (col. 12, line 34 - col. 13,                
          line 24).  Isono’s method differs from that recited in                      
          appellants’ claim 8 in that the rubber tubing segments are not              
          compressed to isolate free ends thereof, the heating is not                 
          produced by induction, and there is no teaching that the ends               
          of the rubber tubing segments are sterilized by the heating.                
               However, Popovich discloses that using clamps to isolate               
          a portion of the connection tubing between a patient and a                  
          dialysis bag permits a potential contamination zone to be                   
          formed (col. 4, lines 53-59), and that heating the portion                  
          between the clamps using ultraviolet radiation permits all of               
          the tubing and tubing connector in the potential contamination              
                                          4-4-                                        





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