Appeal No. 95-3156
Application No. 07/898,348
or a silylating agent having sufficient reactivity to
yield said intermediate.
The references relied on by the examiner are:
Liu et al. (Liu) 4,287,123 Sep. 1, 1981
Christensen et al. (Christensen) 4,290,947 Sep. 22, 1981
T.H. Chan et al. (Chan), ""-t-Butylation of Aldehydes and
Ketones by the Friedel-Crafts Alkylation of Trimethylsilyl
Enol Ethers," Tetrahedron Letters no. 48, 4183-86 (Pergamon
Press Ltd. 1977)
Ian Paterson, "-Alkylation of Ketones, Esters, and Lactones
Zinc Bromide-Catalysed Alkylation of o-Silylated Enolates, A
Synthesis of (±)-AR-Turmerone. Tetrahedron Letters no. 17,
1519-20 (Pergamon Press Ltd. 1979)
M.T. Reetz (Reetz I), Chemical Abstract 95:42446s (1981)
Manfred T. Reetz et al. (Reetz II), tert-Alkylation of Ketones
and Aldehydes, 17 Angew. Chem. Int. Ed. Engl. no. 1, pg. 48-9
(1978)
Jerald K. Rasmussen, "O-Silylated Enolates - Versatile
Intermediates for Organic Synthesis," Synthesis 91, 98 and 99
(Feb. 1977)
S. Oida, "Penems, Synthetic Approach to Thienamycin
Analogues," Ch. 27, pp. 331-48 (1958).
The appealed claims stand rejected as follows: (1)
claims 8 and 22 under 35 U.S.C. § 103 as unpatentable over
Chan, Paterson, Reetz I, Reetz II, or Rasmussen; (2) claim 20
under 35 U.S.C. § 103 as unpatentable over Chan, Paterson,
Reetz I, Reetz II, or Rasmussen, either of those "primary"
references considered in view of Oida, Christensen, or Liu;
-5-
Page: Previous 1 2 3 4 5 6 7 8 9 Next
Last modified: November 3, 2007