Ex parte SCHULTZ et al. - Page 4




          Appeal No. 97-2736                                                           
          Application 08/067,221                                                       


          through 4 and 7 through 9 under 35 U.S.C. § 103, we note that                
          Pritchard discloses a hand held aerosol actuator which                       
          comprises an aerosol source (12, 24, 14, 38) capable of                      
          expelling a turbulent aerosol dose of drug comprising                        
          particles of respirable size, and a chamber (defined within                  
          mouthpiece 22) having walls defining a constriction aperture                 
          (60).  The aerosol source in Pritchard “communicates” with the               
          chamber and comprises an exit orifice (36, 37) that directs                  
          the aerosol along an axis into the                                           




          chamber.  At least a portion of the walls which define the                   
          constriction aperture in Pritchard are “opposite the exit                    
          orifice” and the constriction aperture therein is coaxial with               
          the exit orifice.  As recognized by the examiner (answer, page               
          3), the constriction aperture (60) of Pritchard has a radius                 
          of about 1mm (column 2, lines 31-34) and a cross sectional                   
          area of about 0.03 square centimeters, while the constriction                
          aperture  of appellants’ claimed aerosol actuator is required                
          to have a significantly larger cross sectional area of 0.2 to                
          0.6 square centimeters.                                                      
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