Appeal No. 97-2736 Application 08/067,221 through 4 and 7 through 9 under 35 U.S.C. § 103, we note that Pritchard discloses a hand held aerosol actuator which comprises an aerosol source (12, 24, 14, 38) capable of expelling a turbulent aerosol dose of drug comprising particles of respirable size, and a chamber (defined within mouthpiece 22) having walls defining a constriction aperture (60). The aerosol source in Pritchard “communicates” with the chamber and comprises an exit orifice (36, 37) that directs the aerosol along an axis into the chamber. At least a portion of the walls which define the constriction aperture in Pritchard are “opposite the exit orifice” and the constriction aperture therein is coaxial with the exit orifice. As recognized by the examiner (answer, page 3), the constriction aperture (60) of Pritchard has a radius of about 1mm (column 2, lines 31-34) and a cross sectional area of about 0.03 square centimeters, while the constriction aperture of appellants’ claimed aerosol actuator is required to have a significantly larger cross sectional area of 0.2 to 0.6 square centimeters. 4Page: Previous 1 2 3 4 5 6 7 8 9 NextLast modified: November 3, 2007