Appeal No. 1995-2659 Application 07/896,705 The secondary art fail to disclose a substantial absence of a continuous liquid phase. Brouillard, though teaching a fixed bed, submerges the support material by pumping syrup over a bed of particles and maintaining it at a level above the top of the bed (col. 16, lines 42-45). Matsuzaki merely teaches reforming fats in, for example, a column or fluid bed bioreactor (col. 5, lines 50-52). None of the references teach a porous bed of solid support material in “the substantial absence of a continuous liquid phase”. We are provided no reason why one with ordinary skill in the art would modify Pratt to conduct their process in an agitation-free unsubmerged environment. Since “[o]bviousness can not be established by hindsight combination to produce the claimed invention,” In re Dance, 160 F.3d 1339, 1343, 48 USPQ2d 1635, 1637 (Fed. Cir. 1998), a prima facie case of obviousness has not been established and, accordingly, we reverse the rejection. 11Page: Previous 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 NextLast modified: November 3, 2007