Ex parte HUMPHREY et al. - Page 11



            Appeal No. 1995-2659                                                      
            Application 07/896,705                                                    




                 The secondary art fail to disclose a substantial                     
            absence of a continuous liquid phase.  Brouillard, though                 
            teaching a fixed bed, submerges                                           
            the support material by pumping syrup over a bed of                       
            particles and maintaining it at a level above the top of                  
            the bed (col. 16, lines 42-45).  Matsuzaki merely teaches                 
            reforming fats in, for example, a column or fluid bed                     
            bioreactor (col. 5, lines 50-52).                                         
                 None of the references teach a porous bed of solid                   
            support material in “the substantial absence of a                         
            continuous liquid phase”.  We are provided no reason why                  
            one with ordinary skill in the art would modify Pratt to                  
            conduct their process in an agitation-free unsubmerged                    
            environment. Since “[o]bviousness can not be established                  
            by hindsight combination to produce the claimed                           
            invention,”  In re Dance, 160 F.3d 1339, 1343, 48 USPQ2d                  
            1635, 1637 (Fed. Cir. 1998), a prima facie case of                        
            obviousness has not been established and, accordingly, we                 
            reverse the rejection.                                                    



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