Ex parte BLASS et al. - Page 3


                 Appeal No. 95-3732                                                                                                                     
                 Application 08/172,110                                                                                                                 

                 anterior horn cells where increasing motor strength is sought” (answer, page 4). 5   Appellants dispute                                
                 the examiner’s findings with respect to Bever et al in their brief (page 7) and reply brief (page 2),                                  
                 unchallenged by the examiner.                                                                                                          
                          We find no basis in the statements in the Bever et al article relied on by the examiner,                                      
                 particularly in view of appellants’ arguments, which would lead one of ordinary skill in this art to                                   
                 reasonably conclude that the aminopyridine compounds discussed therein would not have similar                                          
                 pharmacological properties or utility.  Thus, the examiner’s conclusions that the method of treatment                                  
                 specified in the appealed claims is “unpredictable” and “would not necessarily provide appropriate                                     
                 therapy” are indeed clearly speculative in nature as they are unsupported by the record as a whole.                                    
                 Accordingly, the record on this appeal is devoid of a reasonable explanation why the assertions as to                                  
                 the scope of objective enablement set forth in appellants’ specification are in doubt, including reasons                               
                 why the description of the invention therein would not have enabled one of ordinary skill in this art to                               
                 practice the claimed invention without undue experimentation as required by § 112, first paragraph,                                    
                 enablement.                                                                                                                            
















                                                                                                                                                        
                 exposition of the respective positions advanced by the examiner and appellants.                                                        
                 5  The examiner’s conclusion appears to be at odds with her indication that claim 2 of record is objected                              
                 to along with claim 8 of record, apparently because both claims are drawn to allowable subject matter                                  


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