Ex parte ARTER et al. - Page 2




          Appeal No. 95-4298                                                          
          Application No. 07/886,263                                                  


               This appeal was taken from the examiner's decision                     
          rejecting claims 1, 3 through 9 and 11 through 20, which are                
          all of the claims remaining in the application.                             
               Claim 1, which is illustrative of the subject matter on                
          appeal, reads as follows:                                                   
               1.  An analytical element useful for the determination of              
          prostatic acid phosphatase in an aqueous specimen comprising:               
               a porous spreading zone containing                                     
               (a) a nonhygroscopic aromatic phosphate which                          
          reacts as a substrate with prostatic acid phosphatase to                    
          produce a phenol reaction product, said nonhygroscopic                      
          aromatic phosphate substrate being an alkaline earth salt of                
          an aryl phosphate ester, and                                                
               (b) a diazonium or tetrazolium salt which is                           
          capable of reacting with said phenol reaction product to                    
          provide a chromophore,                                                      
               said element further comprising a buffer which maintains               
          said element at a pH of from about 3 to about 6.5 when                      
          contacted with an aqueous specimen.                                         
               The references relied on by the examiner are:                          
          Schnabel et al. (Schnabel)         4,758,508        Jul. 19, 1988           
          Katsuyama                          63-88000         Apr. 19, 1988           
          (Japanese Kokai patent application)                                         
          Marie Pernicova, "Proof of Prostatic Acid Phosphtase Activity               
          in Gel Carriers," Scripta Medica 259-64 (1971)                              



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