Appeal No. 1996-3141
Application No. 08/415,766
Representative Claim
Claim 1, which is illustrative of the subject matter on appeal, reads as follows:
1. An internal surface reverse-phase packing material for liquid
chromatography, comprising a porous particle support having an outer
surface and an inner reverse-phase surface, wherein fatty acid residues are
bonded through ester linkages to form said inner reverse-phase surface.
The References
Horiuchi et al. (Horiuchi) 3,901,763 Aug. 26, 1975
Ayers et al. (Ayers) 4,330,440 May 18, 1982
Pinkerton et al. (Pinkerton)4,544,485 Oct. 01, 1985
Shibata et al. (Shibata) 5,041,226 Aug. 20, 1991
Haginaka et al. (Haginaka), “Internal-Surface Reversed-Phase Silica
Support for Direct Injection Determination of Drugs in Biological Fluids by
Liquid Chromatography”, Anal. Chem., Vol. 61, 1989, pages 2445-2448.
Kirk-Othmer Encyclopedia of Chemical Technology (Kirk-Othmer), 3rd.
edition, Vol. 9, 1980, pages 291 and 300-302.
The Issue
The issue presented for review is whether the examiner erred in rejecting claims 1
through 5 and 17 through 21 under 35 U.S.C. § 103 as unpatentable over Haginaka in view
of Pinkerton, Kirk-Othmer, Ayers, and either Shibata or Horiuchi.
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