Interference No. 102,700
admission, there is a need to screen a large number of
potential sources, by species and tissue type, in order to
identify a suitable source of PAM enzyme. Moreover, according
to Gilligan, identification is further complicated by the fact
that detection of the presence of amidated peptides is not a
reliable indicator of the presence of the enzyme being sought.
It is not seen how the development of a particular
purification technique by Gilligan reduces the uncertainties
involved in identifying a suitable source for purification.
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