Appeal No. 2000-1541 Application 08/608,954 represent that the document discloses that nicotinic acid has a vasodilating effect. The second synopsis relied upon by the examiner appears at page 8, lines 8-30 which in actuality is two different documents. The first document is represented to describe a study involving a patient who after forty years of alopecia showed hair growth after intravenous procaine therapy. The second document is represented to describe a composition which contains a synergistic combination of a number of ingredients including procaine which is “apparently applied topically to improve hair characteristics, but not necessarily hair growth.” Simply put, the evidence relied upon by the examiner does not support the conclusion that persons of ordinary skill in this art understood at the time of the present invention that topical application of procaine and nicotinic acid would serve to stimulate hair growth on the scalp. Any attribution in Szegö that active agents are useful in stimulating scalp or hair bulbs is for the active agent of that reference, not nicotinic acid per se. The so-called admissions set forth in the specification relied upon by the examiner, at best, establish that intravenously administered procaine resulted in hair growth in a single individual. The examiner has not established on this record that the evidence relied upon reasonably teaches that topical application of nicotinic acid and procaine would expectedly result in stimulating hair growth or that merely administering to the scalp 4Page: Previous 1 2 3 4 5 6 7 NextLast modified: November 3, 2007