Ex parte HALLAM et al. - Page 4




               Appeal No. 2000-1541                                                                                             
               Application 08/608,954                                                                                           



               represent that the document discloses that nicotinic acid has a vasodilating effect.  The                        
               second synopsis relied upon by the examiner appears at page 8, lines 8-30 which in                               
               actuality is two different documents.  The first document is represented to describe a study                     
               involving a patient who after forty years of alopecia showed hair growth after intravenous                       
               procaine therapy.  The second document is represented to describe a composition which                            
               contains a synergistic combination of a number of ingredients including procaine which is                        
               “apparently applied topically to improve hair characteristics, but not necessarily hair                          
               growth.”                                                                                                         
                      Simply put, the evidence relied upon by the examiner does not support the                                 
               conclusion that persons of ordinary skill in this art understood at the time of the present                      
               invention that topical application of procaine and nicotinic acid would serve to stimulate                       
               hair growth on the scalp.  Any attribution in Szegö that active agents are useful in                             
               stimulating scalp or hair bulbs is for the active agent of that reference, not nicotinic acid per                
               se.  The so-called admissions set forth in the specification relied upon by the examiner, at                     
               best, establish that intravenously administered procaine resulted in hair growth in a single                     
               individual.  The examiner has not established on this record that the evidence relied upon                       
               reasonably teaches that topical application of nicotinic acid and procaine would                                 
               expectedly result in stimulating hair growth or that merely administering to the scalp                           


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