Ex parte EVANS et al. - Page 12


                  Appeal No. 1995-1977                                                                                       
                  Application 07/669,403                                                                                     



                  heat-inactivated NCS, would be a desirable modification for growing ungulate                               
                  embryonic stem cells.                                                                                      
                         In effect, the instant rejection says that it would have been obvious to vary                       
                  the composition of the growth medium for ungulate embryonic stem cells, even                               
                  though the prior art gives no indication that inclusion of heat-inactivated NCS was                        
                  critical and no direction as to what modifications in the growth medium would                              
                  likely be successful.  This is not obviousness under § 103, but rather an                                  
                  “obvious-to-try” rejection, as discussed in In re O’Farrell, 853 F.2d 894, 903,                            
                  7 USPQ2d 1673, 1681 (Fed. Cir. 1988):  “In some cases, what would have been                                
                  ‘obvious to try’ would have been to vary all parameters or try each of numerous                            
                  possible choices until one possibly arrived at a successful result, where the prior                        
                  art gave either no indication of which parameters were critical or no direction as                         
                  to which of many possible choices is likely to be successful.”  We, therefore,                             
                  reverse this rejection.                                                                                    




















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