Ex parte HARMAN et al. - Page 10


                    Appeal No. 1996-0657                                                                                                    
                    Application 07/919,784                                                                                                  



                            We disagree that Gooday supports a conclusion that it would have been prima facie                               

                    obvious to combine the known endochitinase and chitobiosidase in a weight ratio ranging from                            

                    3:1 to 1:1.2 to form a “biologically pure” anti-fungal composition.  Nor does any disclosure in                         

                    Kuhn which we can find, or which the examiner relies on, including Fig. 1A-E, cure the                                  

                    deficiencies of Gooday.                                                                                                 

                            The Examiner’s Answer, in large part, constitutes an ex post facto effort to explain why                        

                    appellants’ combination of endochitinase and chitobiosidase gives rise to superior anti-fungal                          

                    activity.  In our judgment, however, the applied prior art does not constitute an adequate                              

                    evidentiary foundation to support a conclusion of obviousness of appellants’ claimed                                    

                    composition and method at the time the invention was made.                                                              

                            For these reasons, we conclude that the examiner has not established a prima facie case                         

                    of obviousness of claims 5, 6, 8, 12, and 13 and, accordingly, the rejection of those claims                            

                    under 35 U.S.C. § 103 is reversed.  We find it unnecessary to discuss the rebuttal evidence in                          

                    appellants’ specification, and in the Harman declaration under 37 CFR § 1.132, executed                                 

                    December 23, 1993, relied on to rebut any such prima facie case.                                                        

                            The examiner’s decision is reversed.                                                                            

                                                              REVERSED                                                                      







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