Ex parte BRIDGES et al. - Page 9




              Appeal No. 96-1027                                                                                           
              Application 08/162,288                                                                                       
              constructs with the use of sense constructs, we do not see that a basis has been formed for                  
              combining the references to reach the claimed process.                                                       
                     "To establish a prima facie case of obviousness based on a combination of                             
              references, there must be a teaching, suggestion or motivation in the prior art to make the                  
              specific combination that was made by the applicant."   In re Dance, 160 F.3d 1339, 1343,                    
              48 USPQ2d 1635, 1637 (Fed. Cir. 1998).  While there is no doubt that each of the claimed                     
              limitations are taught by the cited references, the mere fact that the prior art could be                    
              modified to obtain the claimed process does not make the modification obvious unless the                     
              prior art suggested the desirability of the modification.  In re Gordon, 733 F.2d 900, 902,                  
              221 USPQ 1125, 1127 (Fed. Cir. 1984).  Something in the prior art as a whole must                            
              suggest the desirability and thus the obviousness of making the combination.  Lindemann                      
              Maschinenfabrik GmbH v. American Hoist and Derrick Co., 730 F.2d 1452, 1462, 221                             
              USPQ 481, 488 (Fed. Cir. 1984).  Here the examiner has not pointed to anything in the                        
              references which would lead one to the claimed combination and we can find none.  The                        
              only reason for using the partial constructs of Jorgensen in a process like Hiatt's, to modify               
              the expression of fruit-ripening enzymes in plant cells, is provided by appellants' disclosure.              
              It is however impermissible, as examiner has done here, to use appellants' specification                     
              as a blueprint to reach the claimed invention from the prior art disclosures.  "When prior art               
              references require selective combination by the court to render obvious a subsequent                         
              invention, there must be some reason for the combination other than hindsight gleaned                        


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