Ex parte BEN-BASSAT et al. - Page 6





                Appeal No. 1996-2123                                                                                                          
                Application No. 08/069,458                                                                                                    



                                         Thus, the undue practice of many techniques may be required to                                       
                                 practice appellants= claimed invention especially since appellants admit                                     
                                 that stability and low gluconic acid production are not necessarily required                                 
                                 to produce reticulated cellulose (see page 23 lines 1-5, of the instant                                      
                                 Appeal Brief) . . . .  Agitation alone does not provide sufficient criterion                                 
                                 for the production of reticulated cellulose since negative cellulose strains                                 
                                 and mutants are produced under agitated conditions spontaneously and                                         
                                 via the use of specific mutagens.                                                                            
                In response, appellants states:                                                                                               
                                 Appellants believe that this new argument by the examiner reveals a                                          
                                 fundamental misunderstanding of the claimed invention.  The claimed                                          
                                 invention is not directed to using agitation as a method of mutagenesis.                                     
                                 The claims are directed to strains of Acetobacter that are capable of                                        
                                 producing reticulated cellulose under the appropriate conditions.                                            
                See, Reply Brief page 5.                                                                                                      

                We agree with appellants.                                                                                                     
                         In considering the enablement rejection before us for review, we find the following passage from                     
                PPG Indus., Inc. v. Guardian Indus. Corp., 75 F.3d 1558, 1564 37 USPQ2d 1618, 1623 (Fed. Cir.                                 
                1996) relevant:                                                                                                               
                         In unpredictable art areas, this court has refused to find broad generic claims enabled by                           
                         specifications that demonstrate the enablement of only one or a few embodiments and do not                           
                         demonstrate with reasonable specificity how to make and use other potential embodiments across                       
                         the full scope of the claim.  See, e.g., In re Goodman, 11 F.3d 1046, 1050-52, 29 USPQ2d 2010,                       
                         2013-15 (Fed. Cir. 1993); Amgen, Inc. v. Chugai Pharmaceutical Co., 927 F.2d. 1200, 1212-14,                         
                         18 USPQ2d 1016, 1026-28 (Fed. Cir.), cert. denied, 502 U.S. 856 (1991); In re Vaeck, 947 F.2d                        
                         at 496, 20 USPQ2d at 1445.  Enablement is lacking in those cases, the court has explained,                           
                         because the undescribed embodiments cannot be made, based on the disclosure in the                                   
                         specification, without undue experimentation.  But the question of undue experimentation is a                        
                         matter of degree.  The fact that some experimentation is necessary does not preclude enablement;                     
                         what is required is that the amount of experimentation Amust not be unduly extensive.@  Atlas                        
                         Powder Co. v. E.I. DuPont De Nemours & Co., 750 F.2d 1569, 1576, 224 USPQ 409, 413 (Fed.                             
                         Cir. 1984).  The Patent and Trademark Office Board of Appeals summarized the point well when                         
                         it stated:                                                                                                           


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