Ex parte ROMISCH et al. - Page 2




              Appeal No. 1996-2216                                                                                      
              Application No. 08/087,058                                                                                


                            1.  A method for the treatment of inflammatory skin disorders,                              
                     intestinal disorders or purpura which method comprises administering one                           
                     or more complement inhibitors from the group consisting of C1 inactivator,                         
                     factor I and factor H.                                                                             
                            7.  A method as claimed in claim 1, which comprises administering 1-                        
                     5000 IU/kg x day C1 inactivator, 0.005-100 mg/kg x day factor I, or 0.005-                         
                     100 mg/kg x day factor H.                                                                          
                     The references relied on by the examiner are:                                                      
              Pelzer et al. (Pelzer)                    4,915,945            Apr. 10, 1990                              
              Naka et al.   (Naka)                      4,981,855            Jan.   1, 1991                             
              Sims et al.   (Sims)                      5,135,916            Aug.  4, 1992                              
              Glover et al. (Glover)                    5,157,019            Oct. 20, 1992                              
              Lezdey et al. (Lezdey)                    5,166,134            Nov. 24, 1992                              
              Eur. Pat. App.  (EP '611)                 222 611              May 20, 1987                               
              Kitano et al. (Kitano), "New Treatment of Ulcerative Colitis with K-76," Diseases of the                  
              Colon & Rectum, Vol. 35, No. 6, pp. 560-67 (June 1992).                                                   
                                                        ISSUE3                                                          
                     Claims 1, 3, 5 and 7-9 stand rejected under 35 U.S.C. § 103 as being unpatentable                  
              over EP '611, Kitano, Lezdey, Pelzer, Sims, Glover and Naka.                                              
                     We REVERSE.                                                                                        
                     In reaching our decision in this appeal we have given careful consideration to the                 
              appellants' specification and claims and to the respective positions articulated by the                   


                     According to the examiner, the final rejection of claims 1, 3, 5 and 7-9 under 35 U.S.C. § 112, first3                                                                                                 
              paragraph, for lack of enablement was overcome by the amendment filed January 13, 1995 (Paper No. 10)     
              (see the advisory action mailed February 1, 1995 (Paper No. 11)).                                         
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