Appeal No. 1996-2766 Application No. 08/258,909 According to appellants, the invention is directed to compositions and dosage forms for cleaning protein and lipid deposits from the lens surface of contact lens by providing a cleaning composition which increases the pH to a basic level using substantially no protein-digesting enzyme or protein- dissolving surfactant (Brief, pages 2-3). Claim 15 is illustrative of the subject matter on appeal and a copy of this claim is reproduced below: 15. A solid pH-controlled cleaner dosage form, comprising: a) a tonicity builder comprising a water-soluble salt compatible with ocular tissue; and b) a pH regulator selected from the group consisting of basic acetates, phosphates, borates, nitrates, sulfates, tartrates, lactates, carbonates, bicarbonates, and mixtures thereof, whereby dissolution of said pH regulator in an aqueous environment results in a protein cleaning composition having a pH of 7.5 to 11.5, wherein said composition includes substantially no protein-digesting enzyme and wherein a protein-dissolving effective amount of surfactant is absent from said composition. The examiner has relied upon the following references as evidence of obviousness: Fu 4,323,467 Apr. 6, 1982 Davies et al. (Davies) 4,863,627 Sep. 5, 1989 2Page: Previous 1 2 3 4 5 6 7 8 9 10 NextLast modified: November 3, 2007