Appeal No. 1996-2919 Application No. 08/139,861 The examiner relies upon the following references as evidence of obviousness: Tenud 4,021,480 May 03, 1977 Sayo et al. (Sayo) 4,916,252 Apr. 10, 1990 Appellants' claimed invention is directed to a process for preparing a optically active carnitine ester in accordance with formula (I). The process entails asymmetrically hydrogenating the ester halide of formula (II) in the presence of a ruthenium-optically active phosphine complex defined by formulae (III), (IV), (VI) and (VII). The ruthenium-optically active phosphine complex serves as a catalyst for the reaction. The optically active carnitine ester is an intermediate in the production of optically active carnitine, which has medicinal uses. The present application is a continuation of U.S. Application No. 07/455,023, filed December 22, 1989. An appeal was taken to this Board in the parent application and, in a decision dated August 24, 1993, the Board affirmed the examiner's rejection under 35 U.S.C. § 103 over prior art that is presently applied by the examiner. However, the present claims on appeal are narrower in scope than those before the Board in the parent application, and the present record -2-Page: Previous 1 2 3 4 5 6 7 8 9 10 11 12 13 NextLast modified: November 3, 2007