Ex parte TAKETOMI et al. - Page 2




          Appeal No. 1996-2919                                                        
          Application No. 08/139,861                                                  


               The examiner relies upon the following references as                   
          evidence of obviousness:                                                    
          Tenud                            4,021,480          May  03, 1977           
          Sayo et al. (Sayo)               4,916,252          Apr. 10, 1990           
               Appellants' claimed invention is directed to a process                 
          for preparing a optically active carnitine ester in accordance              
          with formula (I).  The process entails asymmetrically                       
          hydrogenating the ester halide of formula (II) in the presence              
          of a ruthenium-optically active phosphine complex defined by                
          formulae (III), (IV), (VI) and (VII).  The ruthenium-optically              
          active phosphine complex serves as a catalyst for the                       
          reaction.  The optically active carnitine ester is an                       
          intermediate in the production of optically active carnitine,               
          which has medicinal uses.                                                   
               The present application is a continuation of U.S.                      
          Application No. 07/455,023, filed December 22, 1989.  An                    
          appeal was taken to this Board in the parent application and,               
          in a decision dated August 24, 1993, the Board affirmed the                 
          examiner's rejection under 35 U.S.C. § 103 over prior art that              
          is presently applied by the examiner.  However, the present                 
          claims on appeal are narrower in scope than those before the                
          Board in the parent application, and the present record                     
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