Appeal No. 1997-0100
Application 08/167,051
DECISION ON APPEAL
This is an appeal under 35 U.S.C. § 134 from the final rejection of claims 5
through 17, 21, 22, 41 and 42, all the claims remaining in the application. Claims 41 and
42 are reproduced as an Appendix to this opinion.
The references relied on by the examiner are:
Patchett at al. (Patchett) 4,483,850 Nov. 20, 1984
Stewart et al. (Stewart I) 4,801,613 Jan. 31, 1989
Stewart et al. (Stewart II) 4,923,963 May 8, 1990
Eur. Pat. App. (Henke I) 0 370 453 May 30, 1990
Eur. Pat. App. (Henke II) 0 413 277 Feb. 20, 1991
Krapcho et al. (Krapcho), “Angiotensin-Converting Enzyme Inhibitors. Mercaptan,
Carboxyalkyl Dipeptide, and Phosphinic Acid Inhibitors Incorporating 4-Substituted
Prolines,” Journal of Medicinal Chemistry, Vol. 31, No. 6, pp. 1148-1160 (1988).
Hock et al. (Hock), “Hoe 140 A New Potent and Long Acting Bradykinin-Antagonist: In
Vitro Studies,” Br. J. Pharmacol., Vol. 102, pp. 769-774 (1991).
Claims 5 through 17, 21, 22, 41 and 42 stand rejected under 35 U.S.C. § 103. As
evidence of obviousness, the examiner relies on Henke I, Henke II, Stewart I, Stewart II,
Hock, Patchett and Krapcho. We reverse the rejection and enter a new ground of rejection
under the provisions of 37 CFR § 1.196(b).
BACKGROUND
As explained in the specification, pages 1 through 3:
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