Appeal No. 1997-0838 Application 08/235,238 We agree with the examiner that, based on the specification, “there could be many other issues that render the prior art unsatisfactory.” Examiner’s Answer, page 9. In our view, appellants’ original disclosure would not convey to persons skilled in the art that “more than 50% LDH activity” represents a limit on the range of LDH activity for a1 1 clinically useful assay. Accordingly, we find no error in the examiner’s determination that the limitation “preserving more than 50% of LDH activity” is not supported by the 1 specification as originally filed. Rejection III of claims 10 and 11 under § 112, first paragraph, is affirmed. CONCLUSION We have affirmed Rejection III of claims 10 and 11 under 35 U.S.C. § 112, first paragraph, and reversed Rejection I of claims 1, 4 through 6, 10, 11, 13, 15 and 16 under 35 U.S.C. § 103, as well as Rejection II of claims 10 and 11 under 35 U.S.C. § 112, first paragraph. Thus, by our action today, claims 1, 4 through 6, 13, 15 and 16 are free of rejection. 8Page: Previous 1 2 3 4 5 6 7 8 9 10 NextLast modified: November 3, 2007