Ex parte KOHDA et al. - Page 4







                     Based upon the above analysis and findings, we conclude that there is an                           
              insufficient nexus between the coating composition of Kohda and those of Hermes and                       
              Takayanagi to provide adequate motivation to substitute their coating compositions for                    
              those of Kohda.                                                                                           
                     The examiner must show reasons that the skilled artisan confronted with the                        
              same problems as the inventor and with no knowledge of the claimed invention, would                       
              select the elements from the cited prior art references for combination in the manner                     
              claimed.  We determine that there is no reason, suggestion, or motivation to combine                      
              the references in the manner proposed by the examiner.  Accordingly, the examiner                         
              has not established a prima facie case of obviousness.  See In re Rouffet, 149                            
              F.3d 1350, 1357, 47 USPQ2d 1453, 1458 (Fed. Cir. 1998).  The rejection of the                             
              examiner is not sustained.                                                                                



















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