Ex parte ROBINSON - Page 3




                     Appeal No. 1997-1670                                                                                                                                              
                     Application 08/098,942                                                                                                                                            


                                The references relied upon by the examiner are:                                                                                                        
                     Pederson et al. (Pederson)                            5,149,797                                  Sep. 22, 1992                                                    
                                                               1                                                                                                                       
                     PCT Application (Foulkes)                                        WO92 13063                                 Aug.  6, 1992                                         
                     Uhlmann et al. (Uhlmann), "Antisense Oligonucleotides: A New Therapeutic Principle,"                                                                              
                     Chemical Reviews, Volume 90, No. 4, pages 543-84 (1990).                                                                                                          
                     Tischer et al. (Tischer), “The Human Gene for Vascular Endothelial Growth Factor,”                                                                                
                     The Journal of Biological Chemistry, Vol. 266, No. 18, pp. 11947-954 (1991).                                                                                      
                     Claffey et al. (Claffey), “Vascular Endothelial Growth Factor,” The Journal of Biological                                                                         
                     Chemistry, Vol. 267, No. 23, pp. 16317-322 (1992).                                                                                                                
                     Kim et al. (Kim), “Inhibition of Vascular Endothelial Growth Factor-Induced Angiogenesis                                                                          
                     Suppresses Tumor Growth In Vivo,” Nature, Vol. 362, pp. 841-43 (1993).                                                                                            
                                                                        GROUND OF RECORD                                                                                               

                                The examiner having withdrawn the rejection of the appealed claims 12-15 and 24,                                                                       
                     under 35 U.S.C.  112, first paragraph, at page 2 of the Examiner's Answer (Answer), the                                                                          
                     sole remaining ground of rejection for consideration in this appeal is the rejection of claims                                                                    
                     8-15 and 23-24 under 35 U.S.C.  103.  As evidence of obviousness, the examiner relies                                                                            
                     on Uhlmann, Peterson, Kim, Foulkes, Claffey, Tischer and page 4 of the applicant's                                                                                
                     specification.                                                                                                                                                    
                                We reverse the rejection under 35 U.S.C.  103.                                                                                                        


                                1 The examiner and appellant have limited their consideration to the file copy of the                                                                  
                     abstract of this reference.  We, therefore, have limited our consideration of this reference                                                                      
                     to this abstract.                                                                                                                                                 
                                                                                          3                                                                                            





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