Ex parte DILLARD et al. - Page 9




          Appeal No. 1997-2184                                                        
          Application 08/278,441                                                      

                        THE REJECTIONS UNDER 35 U.S.C. § 103                          
               We shall reverse each of the examiner's stated reasons                 
          for finding appellants' claimed invention to be unpatentable                
          under 35 U.S.C. § 103.  We find no reference relied on would                
          have fairly suggested appellants' claimed group of indene-1-                
          acetamides and we find no reference on which the examiner has               
          relied would have suggested that appellants' compounds would                
          have been expected to exhibit sPLA  inhibition.                             
                                            2                                         
               We presume the examiner's characterization of the "prior               
          art" as disclosing "a generic group of benzylidene substituted              
          indane compounds" is a reference to the "prior art" on which                
          he relies and while we agree with the examiner's                            
          characterization of that "prior art" as disclosing "a generic               
          group of benzylidene substituted indane compounds", we find no              
          evidence in any of Girard, Shen '902 or Shen '852 of                        
          appellants' particularly substituted indene-1-acetamides.                   
          Specifically, and contrary to the examiner's conclusion, none               
          of the cited prior art discloses at the positions bearing                   
          appellants' R  or R  of the indene moiety an "acidic group"6    7                                                         
          attached to the indene moiety by a linking group.  Rather,                  
          each of the prior art references discloses a "carboxy"                      

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