Appeal No. 1997-2801
Application 08/364,072
wherein:
1
R is hydrogen, methyl or ethyl;
2
R is a hydrocarbon radical selected from straight or branched chain alkyl, cycloalkyl, or
aralkyl of from 1-12 carbons or monocyclic aryl optionally containing 1 or more lower alkyl
substituents of from 1-2 carbon atoms or 1 or more halogen (Cl, F or Br) substituents;
R' is hydrogen or methyl;
R'' is hydrogen or $-methyl;
R''' is hydrogen, "-methyl or $-methyl.
2. A method according to Claim 1 wherein:
1
R is hydrogen or methyl;
2
R is a branched chain alkyl of from 4-8 carbon atoms;
R', R'', R''' are hydrogen.
3. A method according to Claim 1 wherein the compounds are:
17$-(N-tert-butylcarbamoyl)-4-aza-4-methyl-5"-androst-1-en-3-one;
17$-(N-tert-butylcarbamoyl)-4-aza-5"-androst-1-en-3-one;
17$-(N-isobutylcarbamoyl)-4-aza-4-methyl-5"-androst-1-en-3-one;
17$-(N-isobutylcarbamoyl)-4-aza-5"-androst-1-en-3-one;
17$-(N-tert-octylcarbamoyl)-4-aza-4-methyl-5"-androst-1-en-3-one;
17$-(N-tert-octylcarbamoyl)-4-aza-5"-androst-1-en-3-one;
2
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