Ex parte KAMBOJ et al.; Ex parte FOLDES et al. - Page 81


                  Appeal No.  1997-3221                                                                                          
                  Application No.  08/249,241                                                                                    
                                                   Appeal No. 2000-1778                                                          
                                                 Application No. 08/257,029                                                      
                          Claims 28, 43, 44 and 49 are illustrative of the subject matter on appeal and                          
                  are reproduced below:                                                                                          
                          28. A method of assaying a substance for binding to human GluR3, which                                 
                               comprises the steps of:                                                                           
                                  incubating a cellular host, or a membrane preparation derived from                             
                                  said cellular host, with labeled GluR3 ligand to form a ligand/receptor                        
                                  complex, the cellular host having incorporated expressibly therein a                           
                                  heterologous polynucleotide that encodes a human GluR3 selected                                
                                  from the group consisting of human GluR3A and human GluR3B,                                    
                                         removing unbound ligand, and                                                            
                                         measuring the amount of ligand displaced from or remaining in                           
                                         the receptor/ligand complex.                                                            
                          43. A method as claimed in claim 28, wherein the cellular host has                                     
                               incorporated expressibly therein a heterologous polynucleotide that                               
                               encodes human GluR3 selected from the group consisting of human                                   
                               GluR3A and human GluR3B.                                                                          
                          44.  A method as claimed in claim 43, wherein the cellular host has                                    
                          incorporated expressibly therein a heterologous polynucleotide that                                    
                               encodes human GluR3A having the sequence of SEQ ID NO:2.                                          
                          49. A method as claimed in claim 28, wherein the heterologous                                          
                               polynucleotide is plasmid pBS/humGluR3A (ATCC 75218).                                             

















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