Ex parte ALEXANDER et al. - Page 2




              Appeal No. 1997-3330                                                                                     
              Application No. 08/271,870                                                                               




                     The prior art references relied upon by the examiner in rejecting the                             
              appealed claims are:                                                                                     
              Nelson et al. (Nelson)                    4,753,935                   Jun. 28, 1988                      
              Erlanger, “The Preparation of Antigenic Hapten - Carrier Conjugates: A Survey,” Methods                  
              in Enzymology, Vol. 70, pp. 84-104 (1980).                                                               
              (Rose), “Enzyme-Linked Immunosorbent Assay,” Manual of Clinical Laboratory                               
              Immunology, Third Edition, Rose et al., Ed., American Society for Microbiology,                          
              Washington, D.C., Chapter 17, pp. 99-109 (1986).                                                         
              Brinkley, “A Brief Survey of methods for Preparing Protein Conjugates with Dyes, Haptens,                
              and Cross-Linking Reagents,” Bioconjugate Chemistry, Vol. 3, No. 1, pp. 2-13 (1992).                     

                                                      OPINION                                                          
                     In reaching our decision in this appeal, we have given careful consideration to the               
              appellants’ specification and claims, to the applied prior art references, and to the                    
              respective positions articulated by the appellants and the examiner.                                     
                     Rather than reiterate the conflicting viewpoints advanced by the examiner and the                 
              appellants regarding the above-noted rejection, we make reference to the Examiner's                      
              Answer (Paper No. 13, March 17, 1997) for the examiner's complete reasoning in support                   
              of the rejection, and to the appellants’ Brief  (Paper No. 12, filed January 2, 1997)  for the           
              appellants’ arguments thereagainst.  As a consequence of our review, we make the                         
              determinations which follow.                                                                             

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