Ex parte MORI et al. - Page 4




          Appeal No. 1997-3586                                                        
          Application No. 08/240,811                                                  


               Lacking in the present record is any testimony of                      
               one possessing skill in the relevant art which                         
               establishes that appellants' finding that the                          
               claimed catalyst produces stereoisomers of the                         
               products disclosed by Jackson would have been                          
               unexpected. . . .  Furthermore, appellants have not                    
               demonstrated that the different enantiomer produced                    
               by the claimed catalyst is of significance and of                      
               practical advantage in the art.   In re D'Ancicco,                     
               439 F.2d 1244, 169 USPQ 303 (CCPA 1971).  Simply                       
               put, the argument of appellants' counsel that the                      
               property of the claimed catalyst is unexpected is no                   
               substitute for factual objective evidence                              
               establishing such.  In re DeBlauwe, 736 F.2d 699,                      
               222 USPQ 191 (Fed. Cir. 1984); In re Pearson, 494                      
               F.2d 1399, 181 USPQ 641 (CCPA 1974).                                   
          Also, regarding the method claims that are now again before                 
          us, the Board stated at page 5 of the decision that "it is                  
          incumbent upon appellants to present objective evidence of                  
          unexpected results to rebut the prima facie case of                         
          obviousness."                                                               
               In essence, we find that appellants have met their burden              
          of coming forward with objective evidence of nonobviousness                 
          for the claimed method on appeal.  The Declaration and                      
          Supplemental Declaration of Dr. Gohfu Susukamo present                      
          credible evidence that one of ordinary skill in the art, based              
          on the disclosure of Jackson, would not have expected that                  
          cyclo-[(S)-leu-(S)-his] would catalyze the formation of (S)-                
          cyanohydrins, as presently claimed.  While the examiner states              

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