Appeal No. 1997-4145
Application No. 08/361,328
(Paper No. 12)). Claims 11 through 25 and 30 through 32, the only other claims
pending in the application, have been withdrawn from consideration under 37 C.F.R.
§ 1.142(b) as not readable on the elected invention.
Claims 1, 26, 29 and 33 are illustrative and read as follows.
1. A method of producing super-extended DNA, comprising the
steps:
streaming a DNA sample over a supporting surface to provide a DNA
extended to an interkilobase pair distance that exceeds 0.34 :m.
26. A super-extended DNA that has an interkilobase pair distance
greater than 0.34 :m.
29. An extended DNA prepared by gravitationally streaming the
DNA over a supporting surface wherein the DNA is stretched to an
interkilobase pair distance of about 0.34 :m.
33. The super-extended DNA of claim 26 that has an interkilobase
pair distance of between about 0.50 :m and about 60 :m.
The references relied on by the examiner are:
ALBERT L. LEHNINGER (Lehninger), BIOCHEMISTRY, 635-658 (1970).
Matsumoto et al. (Matsumoto), "Light Microscopic Structure of DNA in Solution
Studied by the 4', 6-Diamidino-2-phenylindole Staining Method," Journal of Molecular
Biology, Vol. 152, 501-516 (1981).
Kanda et al. (Kanda), "Isolation of amplified DNA sequences from IMR-32
human neuroblastoma cells: Facilitation by fluorescence-activated flow sorting of
metaphase chromosomes," Proceedings of the National Academy of Sciences, USA,
Vol. 80, 4069-4073 (1983).
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