Ex parte LAZARUS - Page 7




          Appeal No. 1998-2095                                                        
          Application No. 08/460,311                                                  


          an inflammatory response between the graft and the inner wall               
          of the vessel, but that the inflammatory response of the inner              
          wall will inherently result in the attachment of the graft to               
          the inner wall of the vessel.                                               
               Like the appellant, we do not agree with the examiner’s                
          position.  We are informed by appellant’s specification                     
          that the attachment of vascular graft 20 may be accomplished                
          by providing means or material which initiates an inflammatory              
          response in the vessel intima or inner wall (page 22).                      
          Appellant teaches, for example, that the longitudinal and/or                
          circumferential support structures may be constructed of a                  
          material, or may be coated with a material, which induces an                
          inflammatory response.  According to appellant, such materials              
          may include polylactic acids, polyglycolic acids or polyamino               
          acids.  Other materials disclosed as initiating an                          
          inflammatory response include cat gut, cellulose and nylon.                 
          Barone, on the other hand, teaches that the graft or tube 160               
          is made of a material compatible with the patient’s body, e.                
          g., DACRONŽ, TEFLONŽ or TEFLONŽ coated DACRONŽ and porous                   
          polyurethane (col. 6, lines  55-66) and that the tube 160 or                
          securing means 165 may have a coating of biologically inert                 
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