Ex Parte MEDFORD et al - Page 2



                Appeal No.  1999-1215                                                                         
                Application No.  08/401,192                                                                   

                Blumenfeld et al. (Blumenfeld)        WO 92/19732         Nov. 12, 1992                       
                Inoue et al. (Inoue), “Sequence-dependent hydrolysis of RNA using modified                    
                oligonucleotide splints and RNase H,” FEBS Letters, Vol. 215, No. 2, pp. 327-                 
                330 (1987)                                                                                    
                Hélène et al. (Hélène), “Specific regulation of gene expression by antisense,                 
                sense and antigene nucleic acids,” Biochimica et Biohysica Acta, Vol. 1049,                   
                pp. 99-125 (1990)                                                                             

                                         GROUND OF REJECTION1                                                 
                      Claims 35-43 are rejected under 35 U.S.C. § 103 as being unpatentable                   
                over Hélène in view of Blumenfeld and Inoue.                                                  
                      We reverse.                                                                             
                                                DISCUSSION                                                    
                      In reaching our decision in this appeal, we have given careful                          
                consideration to the appellants’ specification and claims, and to the respective              
                positions articulated by the appellants and the examiner.  We make reference to               
                the examiner’s Answer2 for the examiner’s reasoning in support of the rejection.              
                We further reference appellants’ Brief3, and appellants’ Reply Brief4 for the                 
                appellants’ arguments in favor of patentability.                                              
                THE REJECTION UNDER 35 U.S.C. § 103:                                                          


                                                                                                              
                1 Rejections not referred to in Answer are assumed to have been withdrawn. Ex                 
                parte EMM, 118 USPQ 180, 181 (Bd. Pat. App. & Int. 1958).  Accordingly, we                    
                note the examiner withdrew the rejection of claims 35-43 under 35 U.S.C. § 112,               
                second paragraph.                                                                             
                2 Paper No. 16, mailed September 21, 1998.                                                    
                3 Paper No. 15, received July 9, 1998.                                                        
                4 Paper No. 17, received November 24, 1998.                                                   

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