Appeal No. 1999-1393
Application No. 08/242,344
Appeal No. 2000-1778
Application No. 08/257,029
Claims 28, 43, 44 and 49 are illustrative of the subject matter on appeal and
are reproduced below:
28. A method of assaying a substance for binding to human GluR3, which
comprises the steps of:
incubating a cellular host, or a membrane preparation derived from
said cellular host, with labeled GluR3 ligand to form a ligand/receptor
complex, the cellular host having incorporated expressibly therein a
heterologous polynucleotide that encodes a human GluR3 selected
from the group consisting of human GluR3A and human GluR3B,
removing unbound ligand, and
measuring the amount of ligand displaced from or remaining in
the receptor/ligand complex.
43. A method as claimed in claim 28, wherein the cellular host has
incorporated expressibly therein a heterologous polynucleotide that
encodes human GluR3 selected from the group consisting of human
GluR3A and human GluR3B.
44. A method as claimed in claim 43, wherein the cellular host has
incorporated expressibly therein a heterologous polynucleotide that
encodes human GluR3A having the sequence of SEQ ID NO:2.
49. A method as claimed in claim 28, wherein the heterologous
polynucleotide is plasmid pBS/humGluR3A (ATCC 75218).
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