Appeal No. 1999-1393 Application No. 08/242,344 NMDA protein used in a heteromeric receptor complex with NR3 protein of claim 15. Where the examiner fails to establish a prima facie case, the rejection is improper and will be overturned. In re Fine, 837 F.2d 1071, 1074, 5 USPQ2d 1596, 1598 (Fed. Cir. 1988). Accordingly we reverse the rejection of claims 14 and 15 under 35 U.S.C. § 103 as being unpatentable over Monyer in view of Puckett, Schofield and Grenningloh. The rejection of claim 21: The examiner relies (Answer, page 10) upon Sugihara for the teaching of rat homologs of the recited NMDAR1 variants. However, Sugihara does not make up for the deficiencies in the combination of Monyer in view of Puckett, Schofield and Grenningloh, supra. Where the examiner fails to establish a prima facie case, the rejection is improper and will be overturned. In re Fine, 837 F.2d 1071, 1074, 5 USPQ2d 1596, 1598 (Fed. Cir. 1988). Accordingly, we reverse the rejection of claim 21 under 35 U.S.C. § 103 as being unpatentable over Monyer in view of Puckett, Schofield and Grenningloh as applied to claims 14 and 15 above, and further in view of Sugihara. Summary: We reverse the examiner’s rejection of claim 21 under 35 U.S.C. § 112, second paragraph. 116Page: Previous 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 NextLast modified: November 3, 2007