Ex Parte STAMLER et al - Page 1





                    The opinion in support of the decision being entered today was not written for                        
                                publication and is not binding precedent of the Board.                                    

                                                                                         Paper No. 31                     

                               UNITED STATES PATENT AND TRADEMARK OFFICE                                                  
                                                      __________                                                          
                                   BEFORE THE BOARD OF PATENT APPEALS                                                     
                                                AND INTERFERENCES                                                         
                                                      __________                                                          
                               Ex parte JONATHAN STAMLER, JOSEPH LOSCALZO,                                                
                                         DANIEL SIMON and DAVID SINGEL                                                    
                                                      __________                                                          
                                                Appeal No.  2000-0894                                                     
                                              Application No. 08/437,884                                                  
                                                      __________                                                          
                                                       ON BRIEF                                                           
                                                      __________                                                          
                 Before WINTERS, MILLS, and GRIMES,  Administrative Patent Judges.                                        
                 GRIMES, Administrative Patent Judge.                                                                     

                                                DECISION ON APPEAL                                                        
                         This is a decision on appeal under 35 U.S.C. § 134 from the examiner’s                           
                 final rejection of claims 48-66.  Claims 48, 55, and 65 are representative and                           
                 read as follows:                                                                                         
                         48.    A method for delivering a charged nitrogen monoxide species to a                          
                                targeted site in a patient comprising administering to the patient a                      
                                compound comprising an immunoglobulin molecule bonded to at                               
                                least one nitrogen monoxide moiety, wherein the immunoglobulin                            
                                molecule delivers the charged nitrogen monoxide species under                             
                                physiological conditions at the targeted site in the patient.                             






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