Patent Interference No. 103,548 Goldemberg) and propylene glycol (i.e., Goldemberg et al.) are on the list of possible solvents provided for by Lagrange's reissue claim 31. The Goldemberg disclosures suggest that a hair dye formulator would have considered employing a water/solvent medium containing for example ethanol or propylene glycol, among other solvents, for the purpose of increasing dye uptake or as a standard medium for studying the effect of additives on dyes. The disclosures encompass oxidation dyes, which would appear to include the indolines that are set forth in either of Lagrange patent claim 5 or Konrad claim 4. There is a reasonable expectation that when such an indoline is in a water/solvent medium containing ethanol or propylene glycol, it would, like other dyes, show for example an increase in dye uptake. For this reason, it would have been obvious to one of ordinary skill in the art to select the particular water/solvent mixtures set forth in Lagrange reissue claim 31 from the broad genus of mediums encompassed by the presumed prior art, i.e., Lagrange patent claim 5 and Konrad claim 4, in view of the Goldemberg disclosures. Lagrange (LOB 35-37) disputes the relevance of the Goldemberg disclosures on the grounds that it is directed to any dye; that is, it does not specifically disclose indoles or indolines, and does not provide the necessary incentive to substitute Konrad’s carrier with a solvent. The first argument is unpersuasive. The Goldemberg and Goldemberg et al disclosures are very clear in stating that they are describing the effect of formulation factors/conditions and additives as they relate to any dye or any oxidation dye, respectively. To one of ordinary skill reading these references, the indication is that the 61Page: Previous 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 NextLast modified: November 3, 2007