Appeal No. 1996-2756 Application No. 07/987,235 than the closest prior art.” In response, the examiner argues (Answer, bridging paragraph, pages 9-10) that “[i]t is noted that the declaration is directed to support claims to a composition, not claims to a method. The antisense oligonucleotides used in the declaration would have been obvious to the ordinary artisan at the time of the instant invention for the reasons given above….” In our opinion, the examiner has not adequately addressed appellants’ declaration. We remind the examiner that a conclusion of prima facie obviousness does not end a patentability determination under 35 U.S.C. § 103. As set forth in In re Hedges, 783 F.2d 1038, 1039, 228 USPQ 685, 686 (Fed. Cir. 1986): If a prima facie case is made in the first instance, and if the applicant comes forward with reasonable rebuttal, whether buttressed by experiment, prior art references, or argument, the entire merits of the matter are to be reweighed. In re Piasecki, 745 F.2d 1468, 1472, 223 USPQ 785, 788 (Fed. Cir. 1984). To the extent that the examiner argues that the declaration is not relevant to the composition, we note that “[f]rom the standpoint of patent law, a compound and all of its properties are inseparable; they are one and the same.” In re Papesch, 315 F.2d 381, 391, 137 USPQ 43, 51 (CCPA 1963). In this regard, the examiner should have reevaluated her prima facie case after full consideration of the declaration, along with entirety of the facts and arguments of record. Even had a prima facie case of obviousness had been made in the first instance, in view of the evidence of record, such a prima facie case of obviousness of record would not be sustainable. Accordingly, we reverse the rejection of claims 12, 13, 16, 25 and 30-32 under 35 U.S.C. § 103 as being unpatentable over Weinberg in view of Izant. 9Page: Previous 1 2 3 4 5 6 7 8 9 10 11 NextLast modified: November 3, 2007