Ex Parte ALIZON et al - Page 2




              Appeal No. 1997-2528                                                                                      
              Application No. 07/810,908                                                                                

                     Claim 44 is illustrative of the claims on appeal and reads as follows:                             
                     44.    An in vitro diagnostic method for detecting the presence or absence of                      
              antibodies, which bind to antigens of a Human Immunodeficiency Virus Type 2 (HIV-2),                      
              comprising:                                                                                               
                     (a)    contacting a biological sample with one or more isolated polypeptide                        
              expression products of HIV-2 selected from the group consisitng of p12, polymerase,                       
              Q protein, R protein, X protein, env protein, F protein, TAT, and ART;                                    
                     (b)    detecting the formation of antigen-antibody complex between said                            
              polypeptide expression products and antibodies present in the biological sample.                          
                     No prior art references are relied upon by the examiner.                                           
                     Prior art cited by the merits panel:                                                               
              Luciw et al. (Luciw)                      5,156,949                   Oct. 20, 1992                       
              Clavel et al. (Clavel), “Isolation of a New Human Retrovirus from West African Patients                   
              with AIDS,” Science, Vol. 233, pp.343-346 (1986)                                                          
              Ground of Rejection1                                                                                      
                     Claims 44-46 stand rejected under 35 U.S.C. § 112, first paragraph for lack of                     
              enablement.                                                                                               









                     1 The rejection of Claims 44-46 under 35 U.S.C. § 102(b) as anticipated by                         
              Clavel was withdrawn in the Supplemental Examiner's Answer, September 9, 1997.                            

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