Ex Parte WOOD et al - Page 6




              Appeal No. 1997-2828                                                                                      
              Application No. 08/087,548                                                                                



              1996) .  Furthermore, the conclusion that the claimed subject matter is prima facie                       
              obvious must be supported by evidence, as shown by some objective teaching in the                         
              prior art or by knowledge generally available to one of ordinary skill in the art that would              
              have led that individual to combine the relevant teachings of the references to arrive at                 
              the claimed invention.  See In re Fine, 837 F.2d 1071, 1074, 5 USPQ2d 1596, 1598                          
              (Fed. Cir. 1988).  With this as background, we analyze the prior art applied by the                       
              examiner in the rejection of the claims on appeal.                                                        
                     O’Sullivan is relied on by the examiner for the disclosure of the use of numerous                  
              avermectin and milbemycin pesticides for the control of endo-parasites and ecto-                          
              parasites.  O’Sullivan also discloses the topical application of such compositions.                       
              Asato is relied on for the disclosure of “the claim designated compounds as old and                       
              well-known for the utility claimed in the instant application in combination with various                 
              carriers and excipient.”  Answer, pages 8-9.  The examiner relies upon Maienfisch for a                   
              disclosure of the recited class of compounds in combination with “a plethora of                           
              excipient and carriers, and pour-on formulations”.  The examiner suggests that the                        
              “selection of an appropriate solvent system would have been a simple selection from a                     
              group of obvious alternatives available to the skilled artisan.”  Answer, page 9.                         
                     Kieran describes the use of pour on formulations of avermectins and                                
              milbemycins for the control of insects and/or endo-parasites and ecto-parasites.  The                     


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