Appeal No. 1997-2828 Application No. 08/087,548 1996) . Furthermore, the conclusion that the claimed subject matter is prima facie obvious must be supported by evidence, as shown by some objective teaching in the prior art or by knowledge generally available to one of ordinary skill in the art that would have led that individual to combine the relevant teachings of the references to arrive at the claimed invention. See In re Fine, 837 F.2d 1071, 1074, 5 USPQ2d 1596, 1598 (Fed. Cir. 1988). With this as background, we analyze the prior art applied by the examiner in the rejection of the claims on appeal. O’Sullivan is relied on by the examiner for the disclosure of the use of numerous avermectin and milbemycin pesticides for the control of endo-parasites and ecto- parasites. O’Sullivan also discloses the topical application of such compositions. Asato is relied on for the disclosure of “the claim designated compounds as old and well-known for the utility claimed in the instant application in combination with various carriers and excipient.” Answer, pages 8-9. The examiner relies upon Maienfisch for a disclosure of the recited class of compounds in combination with “a plethora of excipient and carriers, and pour-on formulations”. The examiner suggests that the “selection of an appropriate solvent system would have been a simple selection from a group of obvious alternatives available to the skilled artisan.” Answer, page 9. Kieran describes the use of pour on formulations of avermectins and milbemycins for the control of insects and/or endo-parasites and ecto-parasites. The 6Page: Previous 1 2 3 4 5 6 7 8 9 10 11 12 NextLast modified: November 3, 2007