Ex parte SADOFF et al. - Page 1




              The opinion in support of the decision being entered today was not written for publication                    
                                       and is not binding precedent of the Board.                                           
                                                                                       Paper No. 51                         

                               UNITED STATES PATENT AND TRADEMARK OFFICE                                                    
                                                     ____________                                                           
                                    BEFORE THE BOARD OF PATENT APPEALS                                                      
                                                AND INTERFERENCES                                                           
                                                     ____________                                                           
                                  Ex parte JERALD C. SADOFF, STEVEN M. OPAL,                                                
                                      ALAN S. CROSS, and MARK W. BODMER                                                     
                                                     ____________                                                           
                                                 Appeal No. 1997-4275                                                       
                                               Application No. 08/253,217                                                   
                                                     ____________                                                           
                                                        ON BRIEF                                                            
                                                     ____________                                                           
              Before WINTERS, ROBINSON, and MILLS, Administrative Patent Judges.                                            
              ROBINSON, Administrative Patent Judge.                                                                        

                                                DECISION ON APPEAL                                                          

                     This is a decision on the appeal under 35 U.S.C. § 134 from the examiner's final                       
              rejection of claims 1 - 9 and 13 - 16, which are all of the claims pending in the application.                
                     Claims 1 and 13 are illustrative of the subject matter on appeal and read as follows:                  
                     1.      A pharmaceutical composition comprising an antibody to tumor necrosis                          
              factor (anti-TNF) and an antibody to bacterial lipopolysaccharide (anti-LPS) as a                             
              combined preparation for simultaneous mixed, simultaneous separate or sequential use in                       
              the therapy of sepsis.                                                                                        
                     13.     A method for the treatment of sepsis in a human or animal subject, the                         
              method comprising administering to said subject an effective amount of the combination of                     
              an anti-TNF antibody in conjunction with an anti-LPS antibody.                                                






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